D.Sc. (Biology), 1991 (Biochemistry and Nutrition) - Institute of Nutrition, Moscow, Russia.
Ph.D., 1984 (Biochemistry; Space Biology and Medicine) - Institute of Biomedical Problems, Moscow, Russia.
M.S. , 1977 (Biology and Chemistry) - Moscow State University, Moscow, Russia.

Appointments and Research Experience

Research Assistant Professor, Department of Anatomy, Cell and Neurobiology, Marshall University School of Medicine, Huntington, West Virginia.1993-present.
Intracellular calcium, vitamin D and apoptosis. Signaling via calcium and vitamin D receptors in breast cancer and pancreatic beta-cells. Cellular and molecular biology of vitamin D receptors and calbindins. Intracellular calcium and vitamin D endocrine system in space flight and simulated microgravity. Digital video and confocal image analysis.

Senior Research Officer, MRC Mineral Metabolism Research Unit, University of the Witwatersrand Medical School, Johannesburg, South Africa.1992-93.
Biochemistry and molecular biology of vitamin D. Regulation of vitamin D hydroxylases in kidney cells. Vitamin D receptors and vitamin D hydroxylases in naturally vitamin D-deficient mole rats. Rapid actions of 1,25(OH)2-vitamin D3 on Ca2+ channels.

Senior and Lead Scientist, Institute of Nutrition, Academy of Medical Sciences, Moscow, Russia. 1985-92.
Biochemistry and endocrinology of vitamin D: metabolism, receptors, and biological responses. Regulation of calcium metabolism by the vitamin D hormone. Effects of nutrients, mycotoxins on the vitamin D endocrine system. Clinical endocrinology of vitamin D (immunologic, proliferative and inborn rachitic diseases). Vitamin D endocrine system in space flight and modelled microgravity. Nutritional aspects of vitamin D and prevention of rickets.

Visiting Scientist, Department of Biochemistry (Professor A.W. Norman's laboratory), University of California, Riverside, California. 1990.
Biochemistry and molecular biology of vitamin D. Regulation of gene transcription for calbindin-D28k by 1,25(OH)2D3. Posttranslational modifications of the vitamin D receptor. Nongenomic effects of 1,25(OH)2D3. Mechanisms of the antiproliferative action of vitamin D3 analogues.

Postgraduate Student and Scientist, Institute of Biomedical Problems, Ministry of Health, Moscow, Russia. 1980-84.
Hormonal regulation of calcium and bone metabolism in space flight and modeled weightlessness.

Junior Scientist, Institute of Medical Statistics, Ministry of Health, Moscow, Russia. 1977-80.
Biochemistry and toxicology of highly toxic compounds.

Research Support (the past five years)

Current and previously funded grants:
Vitamin D Endocrine System after Short-Term Space Flight, co-P.I., NASA, 1994-96.
Peptide Regulator of Cellular Calcium, collaborator, NSF, 1993-96.
Calbindins and beta-Cell Survival; co-investigator, DARE Fdn., 1994-95.
Video Imaging of Ca2+ and pH in Breast Cancer Cells; P.I., NIH; 07/96-06/99.
Calbindins and Apoptosis After Short-Term Space Flight; co-P.I., NASA, 06/98-05/99.
Apoptosis in Microgravity-Sensitive Organs; co-P.I., NASA, 06/98-05/99.
Digital Video Imaging System; P.I., Marshall Univ. Sch. Med., BMS Research Fund, 06/98 (awarded).

Academic Advising and Teaching Experience

Marshall University:
"Medical Cell and Molecular Biology", 1995-present.
"Cell and Molecular Biology", 1997-present.
"Research in Cellular Processes", 1995-present.
Doctoral Committee Member, 1993-95.
Research Advisor for several Ph.D., graduate, and undergraduate students, 1993-98.

Russian Universities:
Supervisor and Major Professor for four Ph.D. students, 1987-91, Institute of Nutrition, Moscow, Russia.
Senior Lecturer, Moscow State University, 1987-91. Courses in Biochemistry, Endocrinology, Physiology, and Nutrition.
Teaching Assistant, 1981-83, Courses in Biochemistry and Space Biology and Aerospace Medicine, Institute of Biomedical Problems, Moscow, Russia.

Honors and Awards

Researcher of the Year 1988, Sigma Xi, Marshall University Chapter, Huntington, WV.
Visiting Scholar 1998, Marshall University School of Medicine, Huntington, WV.
Member of Graduate Faculty, 1993-present, Marshall University, Huntington, WV.
Recognition Award, the Council Committee on Project SEED of the American Chemical Society, 1995, Washington, DC.
The Welcome Trust Senior Research Fellowship in Medical Sciences in South Africa, 1993-97 (the award was not accepted because of my relocation to USA).
Excellence in Research Award, 1991, Academy of Medical Sciences, Moscow, Russia.
Visiting Researcher Award, 1990, University of California, Riverside, CA.
Excellence in Research Award, 1988, Institute of Nutrition, Moscow, Russia.
Accomplishment Award, 1983, Institute of Biomedical Problems, Moscow, Russia.
Special Recognition Award, 1979, Institute of Medical Statistics, Moscow, Russia.
Government Stipend for Outstanding Scholastic Achievements, 1974-77. Moscow State University, Moscow, Russia.

Membership in Professional Societies, Editorial Boards, and Grant Review Committees

Reviewer for the New Faculty Research Grant Program, Utah State University, 1997, Logan, Utah.
Journal of Nutrition, 1991-92, Moscow, Russia.
Commission for Medical Problems of Nutrition, the USSR Academy of Medical Sciences, 1991-92, Moscow, Russia
Research Review Committee, Institute of Nutrition, 1991-92, Moscow, Russia.
Consultant, 1990-92, Galenika-ICN, Moscow, Russia.
Biochemistry Society (Russia), 1982-92.
Moscow Society of Naturalists (Russia), 1980-92.
Reviewer for Journal of Biological Chemistry; Endocrinology; Endocrine; Biochemistry; Ukraine Biochemical Journal; Journal of Nutrition; Space Biology and Aerospace Medicine.

Publications (Papers and Book Chapters)

1. Sergeev, I.N. and Rhoten, W.B. (1998). Regulation of intracellular calcium in breast cancer cells. Endocrine 9: 321-327.
2. Sergeev, I.N., Rhoten, W.B. and Spirichev, V.B. (1998). Vitamin D and intracellular calcium. In: Subcellular Biochemistry: Fat-Soluble Vitamins. vol. 30, ch. 12. (P. Quinn and V. Kagan, eds.), Plenum Press: N.Y., p.271-297.
3. Sergeev, I.N., Rhoten, W.B. and Norman, A.W. (1997). 1,25-Dihydroxyvitamin D3, intracellular Ca2+ and apoptosis in breast cancer cells. In: Vitamin D: Chemistry, Biology and Clinical Applications of the Steroid Hormone (A.W. Norman, R. Bouillon and M. Thomasset, eds.), Univ. California Printing: Riverside, p. 473-474.
4. Rusnak, F. and Sergeev, I.N. (1997). Lymphocyte's 1,25(OH)2D3 receptors in children with chronic renal failure. In: Vitamin D: Chemistry, Biology and Clinical Applications of the Steroid Hormone (A.W. Norman, R. Bouillon and M. Thomasset, eds.), Univ. California Printing: Riverside, p. 861-862.
5. Sergeev, I.N., Rhoten, W.B., and Carney, M.D. (1996). Calbindins decreased after space flight. Endocrine 5: 335-340; Cover Illustration.
6. Sergeev, I.N. and Rhoten, W.B. (1995). 1,25-Dihydroxyvitamin D3 evokes oscillations of intracellular calcium in a pancreatic -cell line. Endocrinology 136: 2852-2861.
7. Rhoten, W.B. and Sergeev, I.N. (1994). Calbindin-D28k appears to buffer intracellular Ca2+ in butyrate- treated rat insulinoma cells. Endocrine 2: 989-995.
8. Buffenstein, R., Sergeev, I.N., and Pettifor, J.M. (1994). Absence of calcitriol-mediated nongenomic actions in isolated intestinal cells of the damara mole rat (Cryptomys damarensis). General Comp. Endocrinol. 95: 25-30.
9. Pitcher, T., Sergeev, I.N., and Buffenstein, R. (1994) Vitamin D metabolism in the damara mole-rat is altered by exposure to sunlight yet mineral metabolism is unaffected. J. Endocrinol. 143: 367-374.
10. Sergeev, I.N. and Rhoten, W.B. (1994). Video imaging of intracellular calcium in insulinoma cells: effects of 1,25(OH)2D3. In: Vitamin D, a pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications (A.W.Norman, R.Bouillon, and M.Thomasset, eds.), W. de Gruyter: Berlin, pp. 355-356.
11. Rhoten, W.B. and Sergeev, I.N. (1994) Does calbindin-D28k buffer intracellular free calcium? In: Vitamin D, a pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications (A.W.Norman, R.Bouillon, and M.Thomasset, eds.), W. de Gruyter: Berlin, pp. 412-413.
12. Mutema, G., Sergeev, I.N., and Rhoten, W.B. (1994) Regulation of calbindin-D28k by parathyroid hormone in MDBK cells. In: Vitamin D, a pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications (A.W.Norman, R.Bouillon, and M.Thomasset, eds.), W. de Gruyter: Berlin, pp. 404-405.
13. Norman, A.W., Sergeev, I.N., Bishop, J.E., and Okamura, W.H. (1993). Selective biological response by target organs (intestine, kidney and bone) to 1,25-dihydroxyvitamin D3 and two analogs. Cancer Res. 53: 3935-3942.
14. Sergeev, I.N., Buffenstein, R., and Pettifor, J.M. (1993). Vitamin D receptors in a naturally vitamin D- deficient subterranean mammal, the naked mole rat (Heterocephalus glaber): biochemical characterization. Gen. Comp. Endocrinol. 90: 338-345.
15. Buffenstein, R., Sergeev, I.N., and Pettifor, J.M. (1993). Vitamin D hydroxylases and their regulation in a naturally vitamin D-deficient subterranean mammal, the naked mole rat (Heterocephalus glaber). J. Endocrinol. 138: 59-64.
16. Sergeev, I.N. and Norman, A.W. (1992). Vitamin K-dependent -carboxylation of the vitamin D receptor. Biochem. Biophys. Res. Commun. 189: 1543-1547.
17. Norman, A.W., Nemere, I., Zhou, J., Bishop, J.E., Lowe, K.E., Maiyar, A.C., Collins, E.D., Taoka, T., Sergeev, I., and Farach-Carson, M.C. (1992). 1,25(OH)2-Vitamin D3, a steroid hormone that produces biological effects via both genomic and nongenomic pathways. J. Steroid Biochem. Mol. Biol. 41: 231-240.
18. Farach-Carson, M.C., Sergeev, I., and Norman, A.W. (1991). Nongenomic actions of 1,25-dihydroxyvitamin D3 in rat osteosarcoma cells: structure-function studies using ligand analogs. Endocrinology 129, 1876-1884.
19. Norman, A.W., Koeffler, H.P., Bishop, J.E., Collins, E.D., Sergeev, I., Zhou, L.-X., Nemere, I., Henry, H.L., and Okamura, W.H. (1991). Structure-function relationships in the vitamin D endocrine system for 1,25(OH)2D3 analogs. In: Vitamin D: Gene Regulation, Structure-Function Analysis and Clinical Application (A.W.Norman, R.Bouillon, and M.Thomasset, eds.), W. de Gruyter: Berlin, pp. 146-153.
20. Farach-Carson, M.C., Sergeev, I., Zhou, L.-X., and Norman, A.W. (1991). Nongenomic actions of 1,25(OH)2D3 in rat osteosarcoma cells and chick intestinal epithelial cells: structure-function studies of ligand agonist analogs. In: Vitamin D: Gene Regulation, Structure-Function Analysis and Clinical Application (A.W.Norman, R.Bouillon, and M.Thomasset, eds.) W. de Gruyter: Berlin, pp. 157-158.
21. Sergeev, I.N. and Spirichev, V.B. (1991). Interaction of the vitamin D hormone with other vitamins. In, Vitamin D: Gene Regulation, Structure-Function Analysis and Clinical Application (A.W.Norman, R.Bouillon, and M.Thomasset, eds.), W. de Gruyter: Berlin, pp. 728-730.
22. Sergeev, I.N., Arkhapchev, Y.P., and Spirichev, V.B. (1990). Ascorbic acid effects on vitamin D metabolism and binding in guinea pigs. J. Nutr. 120: 1185-1190.
23. Sergeev, I.N. and Spirichev, V.B. (1990). Regulation of 1,25(OH)2D3 (calcitriol) receptor binding by vitamin B6. Biochemistry 55: 1527-1531.
24. Sergeev, I.N., Arkhapchev, Y.P., and Spirichev, V.B. (1990). Vitamin E role in metabolism and binding of the vitamin D hormone. Biochemistry 55: 1989-1995.
25. Sergeev, I.N. and Spirichev, V.B. (1989). Are 1,25-dihydroxyvitamin D3 receptors vitamin K-dependent ones? Biochemistry 54: 1623-1629.
26. Sergeev, I.N. and Spirichev, V.B. (1989). Do 1,25-dihydroxyvitamin D3 receptors depend on vitamin K? Nutr. Res. 9: 725-733.
27. Spirichev, V.B. and Sergeev, I.N. (1988). Vitamin D: experimental research and its practical application. In: Aspects of Nutritional Physiology (Ed. G.H. Bourne) Karger: Basel, pp. 173-216.
28. Sergeev, I.N., Risnic, V.V., Arkhapchev, Y.P., Kodentsova, V.M., and Spirichev, V.B. (1988). Phorbol ester effects on rat renal 25-OHD3-1-hydroxylase activity: possible role of Ca2+/phospholipid-dependent protein kinase (PKC). In: Vitamin D: Molecular, Cellular and Clinical Endocrinology (A.W. Norman ed.), W. de Gruyter: Berlin, pp. 177-178.
29. Sergeev, I.N., Arkhapchev, Y.P., and Spirichev, V.B. (1988). Ascorbic acid effects on 1-OHase and 24- OHase activity in the kidney and 1,25(OH)2D3 receptor binding in the intestinal mucosa of guinea pigs. In: Vitamin D: Molecular, Cellular and Clinical Endocrinology (A.W. Norman ed.) W. de Gruyter: Berlin, pp. 191-193.
30. Sergeev, I.N. and Spirichev, V.B. (1988). Vitamin K role in the interaction of 1,25(OH)2D3 receptors with DNA. In: Vitamin D: Molecular, Cellular and Clinical Endocrinology (A.W. Norman ed.), W. de Gruyter: Berlin, pp. 237- 239.
31. Kodentsova, V.M., Risnic, V.V., Sokolnikov, A.A., Sergeev, I.N., and Spirichev, V.B. (1988). Vitamin D effects on Ca2+-stimulated ATPase activity and protein composition of the rat's skeletal muscle myofibrils. In: Vitamin D: Molecular, Cellular and Clinical Endocrinology (A.W. Norman ed.), W. de Gruyter: Berlin, pp. 762-763.
32. Sergeev, I.N., Arkhapchev, Y.P., Kim, R.K., Kodentsova, V.M., and Spirichev, V.B. (1987). Effects of ascorbic acid on 25-hydroxyvitamin D3 metabolism in kidneys and 1,25-dihydroxyvitamin D3 receptor binding in the intestinal mucosa of guinea pigs. Biochemistry 52: 1867-11874.
33. Ushakov, A.S., Spirichev, V.B., Belakovsky, M.S., Sergeev, I.N., Kaplansky, A.S., and Shvets, V.N. (1984). Vitamin D3 active metabolites as a countermeasure against disorders of calcium-phosphorus metabolism in hypokinetic rats. Aviat. Space Envir. Med. 55: 534-537.
34. Sergeev, I.N., Arkhapchev, Y.P., Linberg, L.F., Blazheevich, N.V., Ushakov, A.S., and Spirichev, V.B. (1984). 25-Hydroxyvitamin D3 metabolism and its regulation in hypokinetic rats. Biochemistry 49: 590-598.
35. Ushakov, A.S., Spirichev, V.B., Sergeev, I.N., Belakovsky, M.S., and Blazheevich, N.V. (1983). Bone tissue of hypokinetic rats: effects of 24,25-dihydroxycholecalciferol and varying phosphorous content in the diet. Aviat. Space Envir. Med. 54: 447-451.
36. Ushakov, A.S., Sergeev, I.N., Belakovsky, M.S., Spirichev, V.B., Kaplansky, A.S., and Shvets, V.N. (1983). Specific regulation of calcium-phosphorus metabolism during hypokinesia and weightlessness by vitamin D3 active metabolites. Physiologist 26: S112-S113.
37. Ushakov, A.S., Spirichev, V.B., Belakovsky, M.S., Sergeev, I.N., and Kondratyev, Y.I. (1982). Calcium- phosphorus metabolism and prevention of its disorders in hypokinetic rats. Physiologiost 25: S45-S48.

    Papers and Book Chapters (Russian):

38. Sergeev, I.N., Spirichev, V.B., Bogoslovskiy, N.A., Korzova, T.L., Morozova, N.A., and Poznanskaya, A.A. (1992). The vitamin D endocrine system and bone tissue mineral metabolism in rats with adjuvant arthritis: effects of 1,25-dihydroxyvitamin D3. Bull. Exp. Biol. Med. 114(11): 510-512.
39. Sergeev, I.N., Terekhina, T.A., and Spirichev, V.B. (1991). A simplified method for the determination of 1,25(OH)2D (calcitriol) in serum. J. Med. Chem. 37(3); 71-72.
40. Novikov, P.V., Sergeev, I.N., and Spirichev, V.B. (1991). The differential diagnostic significance of determination of 1,25(OH)2D3 (calcitriol) receptors in lymphocytes of children with rickets and rickets-like diseases. Pediatrics (4): 20-24.
41. Rusnak, F.I., Naumova, V.I., Sergeev, I.N., and Pletsity, K.D. (1991). Effect of the treatment with 1 - hydroxycholecalciferol (oxidevit) on calcium metabolism, immune status and 1,25(OH)2D3 receptors in lymphocytes of children with glomerulonephritis. Pediatrics (7): 75-78.
42. Klimova, O.A., Sokolnikov, A.A., and Sergeev, I.N. (1991). Calcium and vitamin D metabolism in vitamin B6-deficient rats. J. Nutr. (4): 56-59.
43. Sergeev, I.N. and Spirichev, V.B. (1990). Role of vitamin B6 in regulation of receptors of 1,25(OH)2-vitamin D3 (calcitriol). Bull. Exp. Biol. Med. 112(12): 631-632.
44. Sergeev, I.N., Piliya, N.M., Tutelian, V.A., and Spirichev, V.B. (1990). The mechanism of impairments in calcium metabolism caused by T-2 toxin: role of the vitamin D endocrine system. J. Med. Chem. 36(5): 26-39.
45. Sergeev, I.N., Kravchenko, L.V., Piliya, N.M., and Spirichev, V.B. (1990). Effect of trichothecene mycotoxin deoxynivalenol on calcium homeostasis and vitamin D metabolism and receptor binding in rats. J. Med. Chem. 36(5): 45-48.
46. Sergeev, I.N., Pletsity, K.D., Rusnak, F.I., and Spirichev, V.B. (1990). Effect of 24,25(OH)2D3 (dioxyvit) on calcium metabolism and the immune status in chronic renal insufficiency. J. Med. Chem. 36(4): 17-20.
47. Sergeev, I.N., Piliya, N.M., Kravchenko, L.V., Spirichev, V.B., and Tutelian, V.A. (1990). Calcium and vitamin D metabolism and the xenobiotic metabolism enzymes during chronic action of mycotoxins. J. Nutr. (5): 25-30.
48. Sergeev, I.N., Pletsity, K.D., Rusnak, F.I., and Spirichev, V.B. (1990). Development of vitamin D deficiency and immunologic disorders in children with glomerulonephritis. J. Nutr. (4): 28-31.
49. Rusnak, F.I., Sergeev, I.N., Pletsity, K.D., and Spirichev, V.B. (1990). Efficiency of 24,24-dihydroxyvitamin D3 (dioxyvit) in chronic renal failure in children. In: Problems of Pediatric Nephrology, TGMI: Dushanbe, p 67-73.
50. Sergeev, I.N. (1989). Metabolism and receptors of vitamin D (a review). J. Med. Chem. 35(1): 2-11.
51. Sergeev, I.N., Pletsity, K.D., Rusnak, F.I., and Spirichev, V.B. (1989). 1,25-Dihydroxyvitamin D3 receptors in lymphocytes and levels of T- and B-lymphocytes in patients with glomerulonephritis. J. Med. Chem. 35(4): 117-121.
52. Sokolnikov, A.A., Kodentsova, V.M., and Sergeev, I.N. (1989). Calcium and vitamin D metabolism in vitamin K-deficient rats. J. Nutr. (1): 56-60.
53. Sergeev, I.N. and Pilya, N.M. (1989). Effects of T-2 toxin and aflatoxin B1 on metabolism and biochemical functions of vitamin D. In: Proc. Inst. Nutr. Acad. Med. Sci. USSR, v. 9, p. 84-92.
54. Kondrachin, I.P., Terlikbaev, A.A., Bogoslovsky, N.A., and Sergeev, I.N. (1989). Etiology and pathogenesis of after-birth hypocalcemia in the cow. In: Proc. All-Union Acad. Agric. Sci. (8): 123-127.
55. Sergeev, I.N. (1989). Metabolism of vitamin D. In: Proc. Moscow Soc. Naturalists, v. 52, p. 74-78.
56. Sergeev, I.N. and Spirichev, V.B. (1988). Vitamin K role in the interaction of 1,25-dihydroxyvitamin D3 receptors with DNA. Bull. Exp. Biol. Med. 110 (12): 695-698.
57. Sergeev, I.N., Arkhapchev, Y.P., Kravchenko, L.V., and Spirichev, V.B. (1988). Effects of mycotoxins - aflatoxin B1 and T-2 toxin - on vitamin D3 metabolism and the receptor binding of the vitamin hormonal form - 1,25- dihydroxyvitamin D3 in rats. J. Med. Chem. 34(4): 51-57.
58. Karatabanova, N.A., Arkhapchev, Y.P., Sergeev, I.N., and Spirichev, V.B. (1988). Vitamin D metabolism in rats with exogenous hypercorticoidism. J. Med. Chem. 34(1): 83-86.
59. Kodentsova, V.M., Klimova, O.A., Sokolnikov, A.A., and Sergeev, I.N. (1988). Activities of microsomal enzymes of the guinea pig intestinal mucosa in vitamin D and C deficiency. J. Nutr. (2): 41-44.
60. Kolesova, G.M., Sokolnikov, A.A., Kodentsova, V.M., Klimova, O.A., Sergeev, I.N., and Spirichev, V.B. (1988). Effects of vitamin K deficiency on enzymes of the energy metabolism in the rat. J. Med. Chem. 34(4): 46-51.
61. Spirichev, V.B. and Sergeev, I.N. (1987). Vitamin D. In: Proc. Inst. Nutr. Acad. Med. Sci. USSR, v. 8, p. 59-78.
62. Sergeev, I.N., Kim, R.K., Arkhapchev, Y.P., and Spirichev, V.B. (1987). 25-Hydroxyvitamin D3 metabolism in kidneys and chromatin receptors for 1,25-dihydroxyvitamin D3 in the intestinal mucosa in vitamin B2-deficient rats. J.. Med. Chem. 33(6): 96-103.
63. Sergeev, I.N., Blazheevich, N.V., Kaplansky, A.S., Shvets, V.N., and Spirichev, V.B. (1987). A comparative study of the 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 effects on calcium homeostasis and bone tissue in hypokinesia. J. Med. Chem. 33(1): 100-107.
64. Sergeev, I.N., Kim, R.K., Blazheevich, N.V., and Spirichev, V.B. (1987). Effects of combined vitamin D and E deficiency on calcium metabolism and bone tissue in rats. J. Nutr. (1): 39-43.
65. Sergeev, I.N., Kim, R. K., Arkhapcev, Yu.P., Blazheevich, N.V., and Spirichev, V.B. (1987). Vitamin D endocrine system, calcium metabolism and bone tissue in deficiency of vitamin E and B2. In: Regulation of phosphorus- calcium metabolism (A. Babarykin and V. Bauman, eds.), RMI: Riga, p. 129-138.
66. Belakovsky, M.S., Khaidakov, M.S., and Sergeev, I.N. (1987). Vitamin D and hypokinesia. In: Regulation of phosphorus-calcium metabolism (A. Babarykin and V. Bauman, eds.), RMI: Riga, p. 75-83.
67. Sergeev, I.N. and Spirichev, V.B. (1986). Calcium absorption in the intestine of hypokinetic rats. J. Nutr. (4): 50-54.
68. Arkhapchev, Y.P., Sergeev, I.N., and Spirichev, V.B. (1986). Calcium metabolism and serum concentration of the vitamin D3 active metabolites in rats during the bone reparative regeneration. J. Med. Chem. 32(4): 122-129.
69. Vlasova, T.F., Belakovsky, M.S., Miroshnokova, E.B., Sergeev, I.N., and Spirichev, V.B. (1986). Effect of diets with active vitamin D3 metabolite and varying phosphorus and calcium content on the composition of free amino acids in hypokinetic rats. J. Nutr. (1): 55-59.
70. Belakovsky, M.S., Yuzhanskaya, M.G., Panferova, N.E., Sergeev, I.N., and Spirichev, V.B. (1986) Effects of various levels of UV-radiation on vitamin status in humans. Space Biol. Aerospace Med. (1): 56-61.
71. Sergeev, I.N., Kim. R.K., and Spirichev, V.B. (1986). Metabolism and receptors of vitamin D in deficiency of vitamin C and B2. In: Proc. Inst. Nutr. Acad. Med. Sci. USSR, v.7, p. 179-187.
72. Sergeev, I.N., Afonin, B.V., Blazheevich, N.V., and Morukov, B.V. (1985). Role of the vitamin D3 active metabolites in regulation of calcium metabolism in hypokinetic rats. Space Biol. Aerospace Med. (6): 46-50.
73. Vlasova, T.F., Mirochnikova, E.B., Belakovsky, M.S., and Sergeev, I.N. (1985). Effect of 24,24- dihydroxycholecalciferol on amino acid metabolism in hypokinetic rats. Space Biol. Aerospace Med. (5): 88-89.
74. Kabitskaya, O.E., Savic, Z.F., Kaplansky, A.S., Shvets, V.N., Sergeev, I.N., and Spirichev, V.B. (1984). Effects of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 on growth and remodelling of rat bones during hypokinesia (hystomorphometric study). Space Biol. Aerospace Med. (4): 49-55.
75. Arkhapchev, Y.P. and Sergeev, I.N. (1984). 25-Hydroxyvitamin D3 metabolism in rats with the experimental femoral fracture. J. Nutr. (4): 54-57.
76. Arkhapchev, Y.P., Sergeev, I.N., Blazheevich, N.V., and Spirichev, V.B. (1984). Metabolism of [3H]25- hydroxycholecalciferol in rats with the experimental femoral fracture. J. Med. Chem. 30(1): 96-103.
77. Sergeev, I.N., Arkhapchev, Y.P., and Spirichev, V.B. (1983). Effect of hypokinesia on vitamin D metabolism in rats. Space Biol. Aerospace Med. (2): 68-73.
78. Sergeev, I.N., Arkhapchev, Yu.P., Ushakov, A.S., Belakovsky, M.S., Spitsina, N.E., and Afonin, B.V. (1983). Role of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 in regulation of calcium and bone metabolism in hypokinesia. In: Proc. Inst. Nutr. Acad. Med. Sci. USSR, v. 4, p. 124-132.
79. Sergeev, I.N., Blazheevich, N.V., Spirichev, V.B., and Ushakov, A.S. (1982). The role of 24,25- dihydroxycholecalciferol in bone mineralization in hypokinetic rats. Space Biol. Aerospace Med. (5): 74-77.
80. Sergeev, I.N., Blazheevich, N.V., and Spirichev, V.B. (1982). Effect of 24,25-dihydroxycholecalciferol on the chemical composition of rat bone tissue in hypokinesia. J. Med. Chem. 28(5): 102-108.
81. Blazheevich, N.V., Sergeev, I.N., Arkhapchev, Y.P., and Spirichev, V.B. (1982). Effects of vitamin D3 metabolites - 1,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol - on callus mineralization in rats with femoral fracture. J. Med. Chem. 28(6): 98-105.
82. Blazheevich, N.V., Spirichev, V.B., Ushakov, A.S., and Sergeev, I.N. (1982). Effect of 1- hydroxycholecalciferol and varying phosphorus content in the diet on phosphorus-calcium metabolism in hypokinetic rats. Space Biol. Aerospace Med. (2): 34-40.
83. Belakovsky, M.S., Blazheevich, N.V., Spirichev, V.B., and Sergeev, I.N. (1982). Effect of excessive phosphorus consumption on calcium-phosphorus metabolism and bone tissue in hypokinetic rats. Space Biol. Aerospace Med. (5): 70-73.

    Meetings and Seminars (invited or selected lectures and presentations with abstracts).
    International:
    First International Meeting on Rapid Responses to Steroid Hormones, 1998, Mannheim, Germany.
    Gordon Research Conference "Gravitational Effects on Living Systems", 1998, New London, NH.
    FASEB Meeting "Experimental Biology '98", 1998, San Francisco, California.
    Tenth Workshop on Vitamin D, 1997, Strasbourg, France.
    FASEB Meeting "Experimental Biology '97", 1997, New Orleans, Louisiana.
    Thirty-fifth Annual Meeting of the American Society for Cell Biology, 1995, Washington, D.C.
    Ninth Workshop on Vitamin D, 1994, Orlando, Florida.
    FASEB Conference "Calcium and Cell Function", 1994, Saxton's River, Vermont.
    Fourteenth Federative International Congress of Anatomy, 1994, Lisbon, Portugal.
    The Annual Marshall University Research Day, 1993-98, Huntington, West Virginia.
    First Congress of African Union of Physiological Sciences, 1992, Nairobi, Kenya.
    Eighth Workshop on Vitamin D, 1991, Paris, France.
    Tenth International Symposium on Steroid Biochemistry and Molecular Biology, 1991, Paris, France.
    Sixth European Nutrition Conference, 1991, Athens, Greece.
    First International Congress on "Vitamins and Biofactors in Life Science", 1991, Kobe, Japan.
    Seventh International Symposium on Calcium Binding Proteins in Health and Disease, 1990, Banff, Canada.
    International Symposium on Vitamin B6 and Carbonyl Catalysis, 1990, Osaka, Japan.
    International Conference "Nutrition: Health and Disease", 1990, Moscow, Russia.
    Second International Symposium "Calcium-89", 1989, Prague, Czechoslovakia.
    Eighth Congress of the International Pediatric Nephrological Association, 1989, Toronto, Canada.
    Thirteenth Symposium on Column Liquid Chromatography, 1989, Stockholm, Sweden.
    Seventh Workshop on Vitamin D, 1988, Rancho Mirage, California.
    International Symposium "Chromatography in Biology and Medicine", 1986, Moscow, Russia.
    Eighteenth "Intercosmos" Symposium on Space Biology and Medicine, 1985, Gagra, Georgia. Seventeenth "Intercosmos" Symposium on Space Biology and Medicine, 1984, Brno, Czechoslovakia.
    Sixteenth "Intercosmos" Symposium on Space Biology and Medicine, 1983, Kechkemet, Hungary.
    Fifteenth "Intercosmos" Symposium on Space Biology and Medicine, 1982, Bucharest, Romania.
    Fifth Symposium on Gravitational Physiology of International Union of Physiological Sciences, 1983, Moscow, Russia.
    Fourth Symposium on Gravitational Physiology of International Union of Physiological Sciences, 1982, San Diego, CA.
    Soviet-France Symposium "Space Biology and Medicine", 1982, Moscow, Russia.
    
    Soviet:
    All-Union Conference on Clinical Vitaminology, 1991, Moscow, Russia.
    Galenika - ICN Seminar on Vitamins, 1991, Nabereznii Chelni, Russia.
    Second All-Union Congress of Medical Genetics, 1990, Alma-Ata, Kazakhstan.
    Fifth All-Union Symposium on Molecular Liquid Chromatography, 1990, Yurmala, Latvia.
    All-Union Conference on Pediatric Nephrology, 1990, Vinnitsa, Ukraine.
    Eighth All-Union Conference on Physiology of Kidney and Electrolyte Metabolism, 1989, Kharkov, Ukraine.
    Thirteenth All-Union Conference on Clinical Pathophysiology of Kidneys, 1989, Kaluga, Russia.
    Conference "Modern Trends in Theoretical and Practical Medicine", 1988, Palanga, Lithuania.
    Moscow Society of Naturalists, 1987, 1990.
    Moscow Section of the All-Union Biochemical Society, 1987, 1988, 1991.
    Fourth All-Union Symposium on Molecular Liquid Chromatography, 1987, Alma-Ata, Kazakhstan.
    All-Union Symposium on Lipid Biochemistry, 1987, Alma-Ata, Kazakhstan.
    Symposium "Physiology and Pathology of Calcium Metabolism and its Regulation", 1987, Yurmala, Latvia.
    Commission for Medical Problems of Nutrition, Academy of Medical Sciences of the USSR, 1986, 1988, 1989.
    Fourteenth Gagarinskii Readings "Problems of Aviation and Space Medicine and Biology", 1985, Moscow, Russia.
    Seventh All-Union Conference on Physiology of Kidney and Electrolyte Metabolism, 1985, Chernigov, Ukraine.
    All-Union Symposium on Medical Enzymology, 1986, Makhatchkala, Russia.
    Seventh Symposium on Antivitamins, 1983, Grodno, Belorussia.
    Second All-Union Conference "Clinical Pathophysiology of Kidneys", 1983, Irkutsk, Russia.
    Thirteenth Gagarinskii Readings "Problems of Aviation and Space Medicine and Biology", 1983, Moscow, Russia.
    Seventh All-Union Conference on Space Biology and Aviation and Space Medicine, 1982, Kaluga, Russia.
    

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    Last update: 10/30/98